21-aminosteroid

From May 1993 through December 1994, 660 patients were randomized. The trial was prematurely terminated on the advice of an independent monitoring committee after review of outcome data at a preplanned interim analysis. In 556 fully eligible patients (276 tirilazad, 280 vehicle), the odds ratio of a favorable outcome in favor of tirilazad was (95% confidence interval [CI], to ) for the Glasgow Outcome Scale and (95% CI, to ) for the Barthel Index, after adjustment for imbalances between the groups in preexisting disability, prior stroke, and diabetes.

21-aminosteroid

21-aminosteroid

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21-aminosteroid

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