The core laboratory also houses a Luminex 200 multiplexing instrument with Analyst software for the simultaneous quantitation of a wide array of cytokines, chemokines, and other cellular mediators in a small volume of biological sample. Targeted Metabolomics
Targeted metabolomics is the absolute quantitative assessment of a subset of metabolites often linked to a specific metabolic pathway (glycolysis, TCA cycle), requiring a priori knowledge. The core offers a number of LC and GC-MS/MS based metabolomics panels, including the Biocrates p180 metabolomics kit, acylcarnitines, amino acids, bile acids, free fatty acids, sphingolipids, steroids, and organic acids. The core is well-equipped with six mass spectrometry platforms integrated with either UPLC, nano-LC or GC systems for the routine analysis or the assay development for small molecules and metabolomic panels.