In 2005, a new technology was discovered that uses Cryolipolysis to destroy fat cells without harming any other cells in the process. Crypolipolysis is the science behind the Coolsculpting equipment that was developed and trademarked by Zeliq Aesthetics. Coolsculpting was specifically designed to target and cool only fat cells underneath the skin such as belly fat – literally freezing them to the point of elimination! By only freezing and killing the fat cells, the healthy skin cells remain untouched and healthy! No knives, no suction hoses, no needles, no scars! Once crystallized, your fat cells die and are naturally eliminated which will leave the treated area noticeably thinner .
Separate clinical trials were conducted in both Japan and the USA to evaluate the effect of topical 2% niacinamide in different ethnic groups. A total of 100 Japanese subjects were enrolled in a double-blind, placebo-controlled comparison between two independent balanced groups. Fifty subjects applied the 2% niacinamide moisturizer to the face for 4 weeks and 50 subjects used a placebo moisturizer for 4 weeks, with sebum excretion rate (SER) measurements taken at baseline, week 2, and week 4. In addition, 30 Caucasian subjects were enrolled in a randomized split-face study for 6 weeks with SER and casual sebum levels (CSL) measured at baseline, week 3, and week 6.