A single trial containing 22 patients, with a low risk of bias was included. This trial found that after 24 months, compared with placebo , the use of intratympanic dexamethasone demonstrated a statistically significant improvement in vertigo as defined by a respective improvement in functional level (90% versus 42%), class (82% versus 57%), change in Dizziness Handicap Inventory scores ( versus ) and mean vertigo subjective improvement (90% versus 57%). The treatment regime described by the authors involved daily injections of dexamethasone solution 4 mg/ml for five consecutive days. These results were clinically significant. No complications were reported.
Cocculus Indicus 6CH is a climbing flowering plant which has been purported
to help vertigo. The fruit of the plat produces picrotoxin a
poisonous crystalline plant alkaloid which has a neurotransmitter
stimulatory effect. The only study regarding Cocculus Indicus
6CH on Pub Med (as of 2/1/2008) was a study by Lucertini M et al.
The report was unable to demonstrate in a double-blind study that Cocculus
Indicus helped in reducing flight simulator sickness.
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